Refers to lisinopril: oral tablets

Seek medical attention if these signs of an allergic reaction, and lisinopril hives severe stomach pain, shortness of breath, face, lips, tongue, or throat.

Call your doctor right away if:

  • Dizzy feeling faint may be;

  • little or no urine;

  • swelling, rapid weight gain;

  • fever, chills, body aches, flu symptoms;

  • fatigue, muscle weakness and heart palpitations or irregular heartbeat;

  • psoriasis (a silvery scaling);

  • chest pain or

  • high potassium (slow heart rate, weak pulse, muscle weakness, tingling sensations);

Common side effects may include:

  • cough;

  • dizziness, drowsiness, headache,

  • depressed mood;

  • nausea, vomiting, diarrhea, nausea, or

  • mild itching or rash.

This is not a complete list of side effects and others may occur. Talk to your doctor about the side effects of medical treatment.

Health care professionals

  Refers to lisinopril: oral tablets


Low blood pressure in patients with a higher likelihood of people of sodium depleted intravascular volume. A large study of patients to the "heart" and chest pain, although related lisinopril is questionable.

Lisinopril and angioedema was published penis case possible association between use. Six days lisinopril, a 74-year-old patient complained of penile "swelling". Lisinopril was suspected as the cause of angioedema and resolved. The localized angioedema resolved within a few days of stopping the drug.

Cardiovascular side effects include hypotension (0.6% to 1.0% of patients), and angioedema (0.2% of patients). Angina pectoris, orthostatic hypotension, palpitations and reported in approximately 1% of patients. In heart failure patients are more likely to lower blood pressure. In one study, the incidence of hypotension associated with adverse events was 0.6%, compared to 4% of the CHF.


Renal side effects include the new (mostly mild), or worsening renal failure, which was rare during treatment with ACE inhibitors. Patients with renal artery stenosis should not receive lisinopril or other ACE inhibitors. Proteinuria has been reported.

Patients with renal artery stenosis maintain glomerular efferent arteriolar vasoconstriction, which is blocked by lisinopril.

Although lisinopril may be associated with increased creatinine and urea, have shown that GFR remain unchanged or improve in most patients.

Nervous system

Nervous system side effects include dizziness, or 13%, headache 6% of patients. Paresthesia represented 1% of patients.


A retrospective study was significantly higher discontinuation rate due to angiotensin-converting enzyme inhibitor cough in black patients than in non-black patients (9.6% vs 2.4%).

Some of the materials studied in the treatment of cough with ACE inhibitors. No long-term studies are lacking, the final version of the treatment. Cromolyn has some advantages over most of the data. Other agents studied baclofen, theophylline, sulindac and Benzoate.

Respiratory side effects including reversible cough up 3%. Cough seemed more common in women than in men, but some of the views of women said they cough more often than men. Other side effects include respiratory wheezing limited secondary hypersensitivity to lisinopril.


The increase in serum potassium is associated with a slight decrease in serum aldosterone.

Metabolic side effects are rare, and a mild, often clinically important serum potassium. Lisinopril and other ACE inhibitors appear to have a beneficial effect on plasma insulin level. Cases of hypoglycemia have been reported in diabetic patients treated with ACE inhibitors when both oral hypoglycemic agents or insulin.


Gastrointestinal side effects include diarrhea (4%), nausea (3%) and vomiting (1%). The taste disorders and constipation has been reported in less than 1%. Acute pancreatitis was lisinopril.

Increased sensitivity

Angioedema, face and neck, the affected patients had a history of reactive airway disease in at least two cases of lisinopril. Patients usually present in intestinal angioedema abdominal pain (with or without nausea or vomiting) and in some cases facial angioedema and C-1 esterase level was previously not normal. These symptoms after stopping the ACE inhibitor.

Hypersensitivity to lisinopril and other angiotensin converting enzyme (ACE) inhibitors, may be life-threatening. Angioedema about 0.2% of patients. Angioedema of the face, extremities, lips, tongue, glottis and / or larynx has been reported rarely with ACE inhibitors. Obstructive laryngeal angioedema due to language and lisinopril is a rare, but potentially fatal reaction. In addition, intestinal angioedema in patients treated with ACE inhibitors. It is recommended that all patients with shortness of breath, trouble swallowing, or significant facial angioedema and do not stop treatment immediately ACE inhibitors in general.


Dermatological side effects include rare cases of urticaria, alopecia, herpes zoster, photosensitivity, skin lesions, skin infections, pemphigus, erythema, psoriasis and other cases of severe skin reactions, including toxic epidermal necrolysis and Stevens-Johnson syndrome (causal relationship has not been established).


Hematologic side effects including aplastic anemia, neutropenia was rarely fatal lisinopril and other ACE inhibitors. Henoch-Schonlein purpura case was complicated by polyarthritis lisinopril.

Within seven days of 64-year-old woman with aortic insufficiency, ischemic heart disease, atrial fibrillation and fever and loss of appetite associated with pancytopenia after the start of furosemide, digoxin, warfarin, and lisinopril. Died despite intensive supportive. Autopsy revealed bone marrow aplasia and changes according to hepatorenal failure. There was no evidence of antibodies produced against infection or disease. At least one (reversible) has been reported.


Although angiotensin-converting enzyme found in many areas of the central nervous system, the mechanism of ACE inhibitor-induced frenzy unclear. They are lipophilic and are known to cross the blood-brain barrier. ACE inhibitors have been shown to affect the metabolism of enkephalins and modulate cholinergic activity. Interestingly, in one case, captopril induced hallucinations successfully treated with naloxone.

Psychiatric complications are rarely credited with ACE inhibitors, including memory loss, confusion, drowsiness, irritability and nervousness. A single case of mania was using the Lisinopril is an elderly woman who previously tolerated enalapril.


Side effects associated with use of ACE inhibitors on the liver is a rare syndrome starts with cholestatic jaundice and progresses to fulminant hepatic necrosis and (sometimes) death. Experts recommend discontinuation of the drug if jaundice or markedly raised liver enzymes, serum developed.


Endocrine side effects including case reports syndrome inappropriate secretion of antidiuretic hormone have been reported.


Other side effects include olfactory disorders. .


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